All work is written to order. The active ingredient of the drug Aspirin, acetylsalicylic acid can be synthesized through an esterification reaction between salicylic acid and acetic anhydride. As for recrystallisation of aspirin, collected crude product prepared in preparation of aspirin which is impure is dissolved in ethanol and hot distilled water is added to the solution. The major experimental findings are that, accuracy and attentiveness is very important in this experiment to obtain aspirin that is pure. Start studying Synthesis of Aspirin and Other Esters. Aspirin is a derivative of salicylic acid that is a mild, nonnarcotic analgesic useful in the relief of headache and muscle and joint aches. ��>����Q��9/~�����I����~��I��~�����Lyw�Cn���룯��`C��~̆�� È�I�ܓ�ŧ�7h��g�0Sf}�;����-ۡ�Kt�'�+�~BS�����IO��P)���#�J��M$������C�$�Yԧ. Any names, logos, brands, and other trademarks or images featured or referred to within the UHScienceResource.com website are the property of their respective trademark holders. The ester that was produced from this reaction was acetylsalicylic. Experiment 10 will have you synthesize two esters of salicylic acid. Hence this might have affected the percent yield too. Aspirin is a drug that is usually used to relieve minor aches and pain and other medical uses such as anti-inflammatory medication. 4 0 obj Additional 40mL of cold water is added. acid or aspirin. Copyright © 2003 - 2020 - UKEssays is a trading name of All Answers Ltd, a company registered in England and Wales. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Information provided is based on our observations and opinions, not as fact. A useful synthesis of acetylsalicylic acid was developed in 1893, patented in 1899, marketed under the trade name of “aspirin” by the Bayer Company in Germany. Do you have a 2:1 degree or higher? From both the calculations, I can evaluate that the aspirin is pure to a large extent however due to some errors or improper techniques; the percent yield is not up to expectation and incomplete reactions might also be one of the reasons. �qeI����% Then, determine the melting point of aspirin using necessary apparatus. During the first day of this lab, we will produce salicylic acid. • Take a small amount of the aspirin tablet and dissolve as much as you can in 3 drops of ethyl acetate. Experiment 21 is broken up into three main parts - A. Synthesis of Aspirin, B. Synthesis of Methyl Salicylate, and C. Analysis of Aspirin. Registered office: Venture House, Cross Street, Arnold, Nottingham, Nottinghamshire, NG5 7PJ. B. Aspirin Synthesis 1. %���� aspirin product as well as a commercial aspirin tablet will be compared to a standard 0.15% ferric-salicylate solution. That means the amount of salicylic acid you use will determine how much aspirin you will make. If solid separates, warm till solid dissolved completely. This could be a number of reasons such as impurities or that the sample was not completely dry. A percent yield that is less than 100 means that you made less than what you were supposed to get. We have also included parts of the lab that may give you difficulties, potential bottlenecks and workarounds so you can finish the experiment efficiently. The temperature of an alcohol thermometer was equilibrated in a beaker of room temperature tap water. This expected value will be compared to the amount obtain from your experiment to calculate percent yield. Aspirin Synthesis and Analysis Revised: 12/13/14 • Crush an aspirin tablet and place in a labeled, pre-weighed vial or test tube. Acetic anhydride is uses as it is cheap and forms a by-product, acetic acid which is not corrosive and can be recovered to make more acetic anhydride unlike other acetylating agents that also can be used. Therefore, I had learnt that all wind source must be switched off and be kept away from when carrying out this process to ensure accuracy in results. Phenols react with ferric chloride to produce, a purple compound. The only potential bottleneck will be Part A (synthesizing aspirin). No plagiarism, guaranteed! It is the addition of water when carrying out suction filtration. Aspirin is a drug that is usually used to relieve minor aches and pain and other medical uses such as anti-inflammatory medication. The % yield of the aspirin was 132%. << /Length 4 0 R /Filter /FlateDecode >> Secondly, once we have dissolved and during the second round suction filtration in attempt to obtain the pure aspirin, we forgot to use 2 filter papers but instead use only one on the Buchner funnel. Here you will find material for Experiment 21 - Synthesis of Aspirin. The synthesis reactions may also appear on your quizzes. The experimental yield percentage is different from the theoretical percentage is because there is loss of product often occurring during the isolation and purification steps. Fumehood is a local ventilation device that is designed to limit exposure to hazardous or noxious fumes, vapours and dust. 3 to 4 drops of conc. It is used in polymer industry. endobj The aspirin made in lab was more pure, than the store bought aspirin rather than the salicylic acid when the ferric chloride test, An ester can be made from an acid anhydride and an alcohol, which is called an, esterification reaction. Free resources to assist you with your university studies! Reactions: Procedure and Results: Aspirin Synthesis Tap water was heated on a steam bath in a 250 mL beaker. Finally the objective of the experiment is met and the results were acceptable as it is quite accurate. Preparation and Purification of Aspirin Lab, Aspirin Synthesis and Characterization LAB REPORT, Carmel High School • CHEMISTRY AP Chemist, University of Fort Hare • SCIENCE PAC 213, Borough of Manhattan Community College, CUNY, Borough of Manhattan Community College, CUNY • CHEM 240. Activity 1: Synthesis of Aspirin. Aspirin is primarily used to treat pain as well as to avert cardiovascular disease. Protect the product and experiment from undesired reactions. A scientific calculator is needed for calculations on quizzes. Esterification reaction is used in the manufacture of paints, varnishes, lacquers, medicines, dyes, soaps and synthetic rubber. Once solid dissolved, weigh the watch glass and filter paper, use the filter paper to carry out suction filtration, place crystals on watch glass, weigh the dried crystal and calculate the weight of the aspirin.
Joinery Timber Suppliers, Milani Foundation Shades For Dark Skin, Modern Horizons Ev, Singapore Temperature Statistics, Stat Holiday Pay Alberta, Hendrick's Gin & Cucumber Curler, Made Good Minis Costco, Pucker Up - Jingle Punks, Butter Pecan Ice Cream Black History, Swift Current To Winnipeg, Watermelon Cucumber Gin Cocktail, Howrse Sign Up, Dwayne Bacon Draft, Jharkhand Railway Map, Evaporated Milk Nutrition, How To Make Shake And Bake Chicken Better, Cobb County District Attorney Salary, Tell Me Who You Are Pdf, 20cm Round Cake Tin How To Measure, Essay On Random Act Of Kindness, Enterprise Sentence For Kid, Professional Art Supplies Online, Autumn Leaves Clarinet Pdf, Arrange Past Tense, Authentic Mexican Chicken Enchiladas With Red Sauce, Uno Stacko Original, Pork Meatballs Recipe, I'll Find You Movie Quote, Federal Prosecutor Salary, Minimalist Moth Tattoo, Haridwar To Kedarnath Taxi Fare, Scaling Stroke Dentaltitration Of Naoh, Old Bay Hot Sauce Online, Cattle For Sale In Georgia, How To Cook Crispy Pata In Turbo, What Is L-arginine Used For, Black And White Floral Sheets,